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Collagen Side Effects: What You Need to Know

Collagen has surged in popularity recently due to its numerous benefits of collagen, particularly for improving skin health, supporting joint function, and maintaining overall vitality. As a key protein in the body, collagen is essential for keeping skin elastic, bones strong, and joints flexible[17]. However, like any supplement, collagen may have side effects for some individuals, particularly when taken in high doses or over extended periods.

This article explores the potential side effects of collagen, helping you make informed decisions about incorporating them into your routine.

Key Takeaways:

  • • Collagen is a crucial protein that supports skin elasticity, joint flexibility, and bone strength, making it popular for overall wellness.
  • • Potential side effects of collagen include digestive issues like bloating and diarrhoea, especially with high doses, and possible allergic reactions to animal-sourced collagen.
  • • High doses may cause hypercalcaemia, particularly with marine-based collagen, leading to elevated blood calcium levels.
  • • Individuals with pre-existing kidney conditions or those who are pregnant or breastfeeding should consult a healthcare professional before starting collagen supplementation.

What is Collagen?

Collagen is the most abundant protein in the human body, providing structure and strength to the skin, bones, tendons, ligaments, and other connective tissues[18]. It acts as a scaffold, supporting the integrity of various tissues and ensurin.g their elasticity and strength[6]. Collagen is made up of amino acids, and there are at least 16 different types, but the most common are Types I, II, III and IV [19].

  • • Type I: It is the most common collagen in the body and is found in skin, tendons, bones, and ligaments. It helps maintain skin elasticity and supports strong bones and connective tissues.
  • • Type II: Primarily located in cartilage and is essential for joint health. It works alongside Type I to maintain skin firmness and support blood vessels and organ structure.
  • • Type III: Found in the skin, blood vessels, and internal organs, Type III works alongside Type I to maintain skin firmness and elasticity.
  • • Type IV: Is located in the basal lamina, a layer in the skin’s basement membrane. It supports filtration processes in organs such as the kidneys and maintains tissue structure in the body.

Side effects of Collagen

While collagen is generally considered safe for most people, some individuals may experience side effects, particularly if taken in high doses. Here are some potential side effects to be aware of:

1. Digestive Issues

Some people may experience digestive discomfort. Common symptoms include bloating, diarrhoea, or constipation. This is more likely to occur with higher doses of collagen or in individuals with sensitive digestive systems[20].

Allergic Reactions

Most collagen is sourced from animals: cows, pigs, or fish. Some people are allergic to the proteins found in one or more of those animals and have allergic reactions when using collagen products. Signs include rashes on the skin, itching, or swelling[2].

Hypercalcaemia

Collagen supplements, particularly those sourced from marine origins, can sometimes lead to hypercalcaemia, which is an excessive build-up of calcium in the blood. This overaccumulation of calcium may result in complications, such as an abnormal heart rhythm[4].

Kidney Strain

Collagen is a protein-rich supplement, and excess consumption may strain the kidneys, especially in individuals with pre-existing kidney conditions. High protein levels can be difficult for the kidneys to process, potentially leading to kidney issues[21].

2. Acne or Skin Reactions

The most used products are anti-ageing creams and topical collagen serums; however, most cause skin irritation, breakouts or allergic reactions shortly after use. This poses a rather serious problem for people who have sensitive skin. Patch testing is always advised before using a new skincare product[5].

Unpleasant Taste or Aftertaste

Some collagen supplements, particularly those derived from marine or bovine sources, can have an unpleasant taste or aftertaste. This can make the supplement difficult to consume for some individuals, potentially causing nausea or a lingering bad taste[7].

Who should be cautious when using Collagen?

1. Pregnant and Breastfeeding Women

While there is limited research on the effects of collagen supplementation during pregnancy or breastfeeding, caution is advised. It’s always wise for pregnant or breastfeeding women to consult their healthcare expert before starting any new supplement, including collagen. This ensures the supplement won’t interfere with the baby’s or the mother’s nutritional needs [12][13].

2. People with Certain Medical Conditions

Those with existing medical conditions, particularly chronic illnesses, should consult a doctor before taking collagen. For instance, individuals with kidney problems may need to avoid high-protein supplements, including collagen, as excess protein can strain the kidneys more[1]. Similarly, collagen could affect how some medications work, so it’s crucial to discuss it with a healthcare professional if you’re on prescription drugs[11].

3. People Prone to Digestive Issues

Collagen supplements can sometimes cause digestive discomfort in sensitive individuals. Some users have reported symptoms such as bloating, heartburn, or an upset stomach. Alternatively, you could opt for hydrolysed collagen, which is easier for the body to absorb and digest[14][15].

Conclusion

Collagen supplements have gained immense popularity due to their potential benefits for skin health, joint function, and overall well-being. However, like any supplement, they are not without risks. While many people can safely incorporate collagen into their diets, some may experience side effects, such as digestive discomfort, allergic reactions, or, in rare cases, more serious issues like hypercalcaemia or kidney strain.

It is essential to approach collagen supplementation cautiously, especially for those with a collagen deficiency, pregnant women, breastfeeding, or having underlying health conditions. Consulting with a healthcare provider before starting a new supplement regime is always wise. Ultimately, being informed and understanding collagen’s benefits and potential risks can help individuals make the best health and well-being decisions.

At Nature’s Fix, you can find collagen supplements in various forms, such as Collagen Powder, Capsules, and pills sourced from trusted brands to suit your unique health needs. Always choose high-quality products and seek professional advice to ensure safe and effective supplementation.

FAQ

1. What are some common side effects of collagen supplements?

At Nature’s Fix, you can find collagen supplements in various forms, such as Collagen Powder, Capsules, and pills sourced from trusted brands to suit your unique health needs. Always choose high-quality products and seek professional advice to ensure safe and effective supplementation.

2. How can the side-effect burden be overcome when supplementing with collagen?

Start with a small dosage, and increase as you gain tolerance. Determine quality collagen products. Consultation with a health professional would also help you use collagen safely.

3. Can collagen supplements help with muscle recovery for men?

Yes, collagen for men assists in muscle recovery by supporting tissue repair and reducing joint discomfort after exercise. Collagen helps with muscle and tendon healing, making it particularly beneficial for men engaged in strength training or high-impact sports[9].

4. Are there any known problems with collagen intolerance?

Some people might be sensitive to collagen. This may cause the formation of stomach aches or allergic reactions. If you react this way, stop using collagen and seek the help of a doctor as soon as possible[9].

5. How does collagen relate to pregnancy?

There are limited studies about collagen supplements in pregnancy. If pregnant, seek your doctor’s advice before using collagen[10].

References

1  – https://www.healthline.com/nutrition/collagen-side-effects-on-kidney

2 – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620403/

3  – https://versusarthritis.org/about-arthritis/complementary-and-alternative-treatments/types-of-complementary-treatments/collagen/

4  – https://www.medicinenet.com/what_are_the_side_effects_of_taking_collagen/article.htm

5 – https://www.medicinenet.com/what_are_the_side_effects_of_taking_collagen/article.htm

6 – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432532/

7 – https://ift.onlinelibrary.wiley.com/doi/full/10.1111/1750-3841.16822

8 – https://versusarthritis.org/about-arthritis/complementary-and-alternative-treatments/types-of-complementary-treatments/collagen/

9  – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521576/

10  – https://www.vinmec.com/eng/article/can-pregnant-women-take-collagen-en

11 – https://www.healthline.com/nutrition/collagen-side-effects-on-kidney#should-you-avoid-it

12 – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294936/

13 – https://www.parents.com/can-i-take-collagen-while-breastfeeding-8655405#

14 – https://www.medicinenet.com/what_are_the_side_effects_of_taking_collagen/article.htm

15 – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891674/

16 – https://www.healthline.com/nutrition/collagen

17 – https://my.clevelandclinic.org/health/articles/23089-collagen

18 – https://my.clevelandclinic.org/health/articles/23089-collagen

19 – https://my.clevelandclinic.org/health/articles/23089-collagen

20 – https://www.medicinenet.com/what_are_the_side_effects_of_taking_collagen/article.htm

21 – https://www.healthline.com/nutrition/collagen-side-effects-on-kidney

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