Designs for Health Ultra B12-Folate is a targeted dietary supplement that combines two essential B vitamins—vitamin B12 and folate—in their most active, bioavailable forms. It uses methylcobalamin and adenosylcobalamin for B12, alongside Quatrefolic® (a highly absorbable form of 5-MTHF folate). Together, these nutrients support the body’s methylation cycle, which is involved in DNA synthesis, detoxification, neurotransmitter production, and energy metabolism. The formula is also commonly used to help maintain healthy homocysteine levels, which are linked to cardiovascular and neurological health. Each capsule provides a high-potency dose designed for daily use, typically taken with food. Additional benefits may include support for red blood cell formation, nervous system function, and overall energy production. Because it uses active vitamin forms, it is often chosen for better absorption compared to standard folic acid or cyanocobalamin supplements.
Certificates: GMP
Made in: USA
Pack size: 90 Capsule
Servings per container: 90
Serving size: 1 capsule
Gender: Men, Women
Primary Ingredients
Vitamin B12 (as Methylcobalamin & Adenosylcobalamin)
Other ingredients
Folate (as Quatrefolic® [65]-5-Methyltetrahydrofolate, Glucosamine Salt), Bulking Agent (Microcrystalline Cellulose), Cellulose (Capsule), Anti-Caking Agent (Vegetable Stearate)

What is Ultra B12-Folate used for?
It is a high-potency B vitamin supplement designed to support energy production, nervous system health, red blood cell formation, and methylation processes involved in DNA synthesis and detoxification.
What forms of B12 and folate does it contain?
It contains active forms of vitamin B12 (methylcobalamin and adenosylcobalamin) and folate as Quatrefolic® (5-MTHF), which are highly bioavailable and ready for use by the body.
Who is this supplement suitable for?
It is commonly used by individuals looking to support energy levels, cognitive function, cardiovascular health, or those with increased B vitamin needs. It is often chosen in practitioner-led nutrition plans.
Take 1 capsule per day with a meal or as directed by your health-care practitioner
Store at room temperature
DisclaimerFood supplements should not be used as a substitute for a varied diet. If you are taking prescribed medication, have any medical condition, or are pregnant or breastfeeding, please consult your healthcare practitioner before taking food supplements.
Free UK Standard delivery on orders £45+
Standard delivery is £4.40 for orders under £45
Express delivery is £5.49 for orders under £45
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Standard (by DPD, pre-cleared, no additional charges) prices start from £6.
Express (by DPD, pre-cleared, no additional charges) prices start from £17.49.
Standard (by regular post, estimated 4 – 21 working days) prices start from £8
Courier (by road, estimated 3 – 7 working days) prices start from £15
Express (by air, estimated 1 – 5 working days) prices start from £20.49
Nature's Fix operate a no quibble 14 day return policy*
Additionally, the CCR give you the right to change your mind and cancel an order within 14 calendar days for any reason.
*Nature’s Fix accepts returns of products returned in perfect re-saleable condition i.e. in original, undamaged packaging, not used, with protective seal in place.
If you do decide to cancel your order or you wish to return an item, then you must put this in writing. The most efficient method would be to email help@naturesfix.co.uk with your order number and “return request” in the subject of the email. You should then await authorisation and further instructions.
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